Oxandrolone increases free and bound cortisol levels, most likely due to its actions as a cortisol receptor antagonist (7). Additionally, oxandrolone decreases thyroid binding globulin concentrations pretty severely with large increases in thyroxine-binding prealbumin resulting in increased T3 uptake (7). This correlates with the belief that oxandrolone is beneficial in a “cutting stack”. Further evidence comes from studies showing a 4 pound decrease in fat mass with a gain of 7 pounds of lean mass over the course of 12 weeks of treatment with only 20 mg (10 mg, twice daily) of oxandrolone (8). There is also evidence in the literature that oxandrolone enhances ketogenesis (9).
Equipoise has one of the longest detection times of any anabolic steroid; if you are a tested athlete you are urged to forgo its use. Equipoise can be detected in the urine for months even after use has been discontinued; some studies have claimed they can trace the drug back to as far as one year from the end of use. In most countries Equipoise is not legally obtainable; in most cases only through purchase from an underground lab can this drug be obtained. For that reason it is very important you understand the laws in the country you live.