WinstrolÂ® is a popular brand name for the anabolic steroid stanozolol. This compound is a derivative of dihydrotestosterone, although its activity is much milder than this androgen in nature. It is technically classified as an anabolic steroid, shown to exhibit a slightly greater tendency for muscle growth than androgenic activity in early studies. While dihydrotestosterone really only provides androgenic side effects when administered, stanozolol instead provides quality muscle growth. Admittedly the anabolic properties of this substance are still mild in comparison to many stronger compounds, but it is still a reliable builder. Its efficacy as an anabolic could even be comparable to Dianabol, however WinstrolÂ® does not carry with it the same tendency for water retention. Stanozolol also contains the same c17 methylation we see with Dianabol, an alteration used so that oral administration is possible. To spite this design however, there are many injectable versions of this steroid produced. Structurally stanozolol is not capable of converting into estrogen. Likewise an antiestrogen is not necessary when using this steroid, gynecomastia not being a concern even among sensitive individuals. Since estrogen is also the culprit with water retention, instead of bulk WinstrolÂ® produces a lean, quality look to the physique with no fear of excess subcutaneous fluid retention. This makes it a favorable steroid to use during cutting cycles, when water and fat retention are a major concern. It is also very popular among athletes in combination strength/speed sports such as Track and Field. In such disciplines one usually does not want to carry around excess water weight, and may therefore find the raw muscle-growth brought about by WinstrolÂ® quite favorable over the lower quality mass gains of more estrogenic agents. Have been noticed when trying to administer these products, even when using a large 22-gauge needle. But there are both advantages and disadvantages to each type of product. On the one hand the large particle size would form a longer acting deposit (depot) while the steroid dissolves, giving us the option of fewer injections. A larger shot every three to four days would likely be sufficient to keep blood levels within limits, which is a favorable schedule for a water-based product. On the other hand we are forced to use a standard size oil
The first isolation and structure identifications of prednisone and prednisolone were done in 1950 by Arthur Nobile .    The first commercially feasible synthesis of prednisone was carried out in 1955 in the laboratories of Schering Corporation, which later became Schering-Plough Corporation , by Arthur Nobile and coworkers.  They discovered that cortisone could be microbiologically oxidized to prednisone by the bacterium Corynebacterium simplex. The same process was used to prepare prednisolone from hydrocortisone . 
For most men an Anavar cycle will be best served for the cutting process or dieting phase; the phase in-which an individual is looking for a ripped physique. This is not a steroid that will serve this purpose to as strong a degree as Trenbolone or even Equipoise nor will it have the same efficiency as Winstrol and many other DHT steroids such as Masteron but it can have a positive effect that is present in a mild form. An Anavar cycle during a cutting diet phase can greatly aid in preserving lean tissue while on a calorie restricted diet as well as increase total metabolic activity; further, when lean enough it can give a physique a bit of a harder appearance. Most men who supplement with Oxandrolone for this purpose will find 50mg per day to generally be a good starting point with 80mg per day being generally safe. Yes, you can take more but much past the 100mg per day range is not going to do a lot more for you; further, as this steroid can cost at least $2 per 10mg tab and often higher an Anavar cycle for a man can get very expensive.