10 mg orally twice per day
Comments: Response to therapy should be evaluated by week 12. If a patient has not lost at least 5% of baseline body weight, discontinue this drug as it is unlikely the patient will achieve and sustain clinically meaningful weight loss with continued treatment.
Use: Adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obese) OR 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbidity such as hypertension, type 2 diabetes mellitus, or dyslipidemia.
Heavy consumption of the essential amino acid lysine (as indicated in the treatment of cold sores) has allegedly shown false positives in some and was cited by American shotputter C. J. Hunter as the reason for his positive test, though in 2004 he admitted to a federal grand jury that he had injected nandrolone.  A possible cause of incorrect urine test results is the presence of metabolites from other AAS, though modern urinalysis can usually determine the exact steroid used by analyzing the ratio of the two remaining nandrolone metabolites. As a result of the numerous overturned verdicts, the testing procedure was reviewed by UK Sport . On October 5, 2007, three-time Olympic gold medalist for track and field Marion Jones admitted to use of the drug, and was sentenced to six months in jail for lying to a federal grand jury in 2000. 
Oral estradiol valerate is used primarily in Europe , under the brand name Progynova.  Although previously available in the United States ,  oral estradiol valerate is no longer available in this country (except in combination with dienogest as a combined oral contraceptive under the brand name Natazia ).  Intramuscular estradiol valerate is available under the brand name Delestrogen in the .  and Canada and under the brand name Progynon Depot in Europe and elsewhere in the world.  In the ., it is available in formulations of 10 mg/mL, 20 mg/mL, and 40 mg/mL in oil (as Delestrogen, as well as generics ).  The only other injectable formulations of estrogen available in the . are estradiol cypionate (5 mg/mL in oil) and conjugated estrogens ( Premarin ) (25 mg/vial in solution).