Endocrine side effects have included inhibition of endogenous testosterone release by means of feedback inhibition of pituitary luteinizing hormone (LH). Large doses of exogenous anabolic steroids may suppress spermatogenesis through inhibition of pituitary follicle stimulating hormone (FSH). The androgenic activity of anabolic steroids may decrease levels of thyroxin-binding globulin and result in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged and there is no clinical evidence of thyroid dysfunction. [ Ref ]
Anapolon is available in injection form, the dosage of 50 , dosages used from 50 to 200 mg per day. Surprisingly, Anadrol therapeutic dosage much higher and sports is 1-5 mg per kilogram body weight per day! If you follow this recommendation, an athlete weighing 100 kg should take 500 mg of anabolic per day. But many bodybuilders will never accept even the most experienced users. There is some evidence that using a dosage of 300 or more mg/day, far less water is accumulated and the drug shows a strong quality of fat burner. However, such dosage should be treated with caution, and there is a lot of products suitable for cutting.